How much pterostilbene should i take?

Pterostilbene extract, a compound that occurs naturally in blueberries and grapes, has attracted considerable attention lately due to its health advantages. As an increasing number of individuals express interest in adding this antioxidant to their daily habits, a frequent inquiry emerges: How much pterostilbene should I take? Rebecca Bio-Tech's blog intends to offer a thorough examination of pterostilbene dosage guidance grounded in current scientific investigations and professional insights.

Before exploring precise dosage guidelines, it's vital to recognize that pterostilbene is a relatively new focus of inquiry within the scientific realm. While hopeful studies exist, many of the potential advantages and optimal dosages are still under exploration. As is the case with any supplement, it is imperative to exercise caution and seek the advice of a healthcare professional when using it.

For General Health And Antioxidant Support

A normal daily dose of pterostilbene is between 50 and 150 mg for people who want to include it in their routine for overall health and antioxidant support. This dosage is often considered safe for most adults and may provide antioxidant benefits and support overall well-being.

The reasoning behind this dosage interval is influenced by various elements. Firstly, pterostilbene bears a structural resemblance to resveratrol, a renowned antioxidant present in grapes and wine. Nevertheless, research indicates that pterostilbene extract boasts higher bioavailability and a prolonged half-life within the body compared to resveratrol. Consequently, smaller quantities might suffice to obtain comparable advantages.

A research article featured in the Journal of Toxicology revealed that daily doses up to 250 mg were well-accepted among healthy adults during a short-term study. Nonetheless, for prolonged use on a daily basis, lower dosages are frequently suggested as a precautionary approach.

It is important to recognize that the impact of antioxidants like pterostilbene can accumulate over time. This suggests that regular, moderate dosages might yield greater benefits than infrequent high doses. Some specialists recommend initiating with a modest dose, approximately 50 mg daily, and gradually escalating as necessary while observing for any possible adverse effects.

For Cognitive Support And Aging

As we grow older, preserving cognitive abilities becomes crucial. Some studies indicate that pterostilbene extract might possess neuroprotective characteristics and may help in promoting brain wellness. For cognitive enhancement and addressing age-associated decline, research has examined dosages varying from 100 to 250 mg per day.

A significant study published in the Journals of Gerontology Series A: Biological Sciences and Medical Sciences evaluated its impact on cognitive abilities in older rats. The dosage used was approximately equivalent to 120 mg per day for the average adult human. The findings revealed enhancements in cognitive performance and cellular stress resilience.

In another investigation featured in Neurobiology of Aging, the effects of pterostilbene on age-induced cognitive decline in mice were studied. The dosage used was roughly equivalent to 200 mg per day for humans. Improvements were noted in working memory along with other cognitive assessments.

It is critical to remember that while these animal studies show promise, further research is essential to validate these effects in humans and to determine ideal dosages. Nevertheless, grounded in these investigations and expert insights, a dosage range of 100 to 250 mg per day is frequently recommended for potential cognitive assistance.

When incorporating pterostilbene for cognitive well-being, it is generally advisable to split the daily dosage into two or three smaller portions throughout the day. This method may contribute to more stable levels in the body. For instance, if one is taking 200 mg daily, they might choose to take 100 mg in the morning and another 100 mg in the evening.

For Specific Health Concerns

Research has delved into higher amounts of pterostilbene extract, ranging from 250 to 500 mg daily, aimed at more specific outcomes such as enhancing cholesterol figures or regulating blood sugar levels. Nevertheless, it is essential to emphasize that such elevated doses should only be pursued under the careful oversight of a healthcare professional, as they might elevate the likelihood of adverse effects.

A publication in the journal Evidence-Based Complementary and Alternative Medicine examined the influence of pterostilbene on lipid profiles in individuals with high cholesterol. The research utilized doses of 125 mg twice a day (250 mg in total) and 50 mg twice a day (100 mg in total). Both doses demonstrated improvements in LDL cholesterol and overall cholesterol, with the larger dose revealing more pronounced results.

Another investigation featured in the Journal of Toxicology assessed its safety and effectiveness in adults with raised LDL cholesterol. This research employed doses of 125 mg twice daily (250 mg total) and noted enhancements in blood pressure and body weight. However, it also reported a slight rise in LDL cholesterol in some participants, underscoring the necessity of medical guidance when administering higher doses.

Concerning blood glucose regulation, a study published in Food & Function explored its effects on insulin sensitivity in obese rats. This research applied a dose equivalent to about 300 mg daily for an average adult human and found improvements in insulin sensitivity and glucose tolerance.

While these investigations indicate potential advantages at heightened doses, it is vital to navigate such levels with care. 

Considerations

When evaluating the use of pterostilbene supplements, various essential aspects should be considered:

①Consult with a medical expert: This is vital, particularly if you have pre-existing medical issues or are on other prescriptions. Pterostilbene could interact with specific medications, especially those processed by the liver. A healthcare professional can assist in determining potential risks and advantages based on your unique health background.

②Supplement quality: The purity and quality of pterostilbene extract can vary widely among different brands. Seek out items from reputable manufacturers that engage in third-party verification for purity and strength.

③Dose timing: Some studies indicate that ingesting pterostilbene alongside a meal that contains some fat may boost its absorption. Nevertheless, further research is necessary to establish the ideal timing for intake.

④Possible side effects: Although it is generally well-received, some individuals may encounter side effects, particularly at elevated doses. These can include stomach discomfort, headaches, and lightheadedness. If you notice any negative effects, cease use and consult your healthcare practitioner.

⑤Long-term usage: The long-term implications remain unclear. While short-term investigations have shown potential, additional studies are required to clarify the safety and effectiveness of prolonged usage.

Pterostilbene Extract For Sale

For those interested in purchasing pterostilbene extract, Rebecca Bio-Tech offers a professional manufacturing solution. As a reputable pterostilbene extract manufacturer, they provide competitive pricing direct from the manufacturer.

Rebecca Bio-Tech prides itself on producing high-quality pterostilbene extract using advanced manufacturing processes. Their commitment to quality control ensures that customers receive a product that meets strict standards for purity and potency.

For those interested in learning more about Rebecca Bio-Tech's pterostilbene extract or to inquire about pricing and availability, you can contact them directly at information@sxrebecca.com. Their team can provide detailed information about their products, manufacturing processes, and any certifications or quality assurances they offer.

References

1. Riche, D. M., McEwen, C. L., Riche, K. D., Sherman, J. J., Wofford, M. R., Deschamp, D., & Griswold, M. (2013). Analysis of safety from a human clinical trial with pterostilbene. Journal of Toxicology, 2013, 463595.

2. Joseph, J. A., Fisher, D. R., Cheng, V., Rimando, A. M., & Shukitt-Hale, B. (2008). Cellular and behavioral effects of stilbene resveratrol analogues: implications for reducing the deleterious effects of aging. Journal of Agricultural and Food Chemistry, 56(22), 10544-10551.

3. McCormack, D., & McFadden, D. (2013). A review of pterostilbene antioxidant activity and disease modification. Oxidative Medicine and Cellular Longevity, 2013, 575482.